ncRNA name | mmu-miR-29b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Mus musculus |
Tissues/Cell_line | mouse Müller cells |
Methods | qPCR, Western blot, CHIP, transfection, MTT assay, flow cytometry, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | miR-29b controled MIAT to regulate its expression and MIAT overexpression suppressed miR-29b.MIAT suppression reversed the effect induced by high glucose, however, miR-29b knockdown reversed the effects induced by MIAT suppression. |
PubMed ID | 28246353 |
Year | 2017 |
Title | Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis. |
Drug-related ncRNA | NO |
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